Maintenance of the STa structure, especially the epitope topology in fusions or conjugates is believed to be important in eliciting neutralizing anti-STa antibodies (communication with Dr
Maintenance of the STa structure, especially the epitope topology in fusions or conjugates is believed to be important in eliciting neutralizing anti-STa antibodies (communication with Dr. elicited protective ABT-639 anti-STa antibodies after being fused to a porcine-type LT toxoid [pLT(R192G)]. In this study, we substituted the 8th, 9th, 16th, or the 17th amino acid of…