We and others have shown that at this molar ratio, PF4 and UFH form high molecular weight complexes (>670 kDa), with each complex capable of binding as many as three antibody molecules [10]
We and others have shown that at this molar ratio, PF4 and UFH form high molecular weight complexes (>670 kDa), with each complex capable of binding as many as three antibody molecules [10]. are dynamic and mutable. Heparin removes cell surface-bound PF4 in most individuals, but removal is incomplete in those with high pre-exposure surface-bound…