Zero penumbra or lesions had been observed in rats receiving control IgG
Zero penumbra or lesions had been observed in rats receiving control IgG. missing both CDC and antibody-dependent mobile cytotoxicity (ADCC) effector features. Finally, lesion size was reduced after macrophage depletion with clodronate liposomes significantly. These outcomes: set up a robust, passive-transfer style of NMO in rats that will not require pre-existing complement or neuroinflammation administration;…