In response, the placenta secretes soluble substances into the maternal circulation which are responsible for the symptomatic phase of the disease
In response, the placenta secretes soluble substances into the maternal circulation which are responsible for the symptomatic phase of the disease. Each of these factors has been shown to induce hypertension experimentally through the production of endothelin-1 (ET-1), a powerful vasoconstrictor. Antagonism of the endothelin-A receptor has Merimepodib proved beneficial in numerous animal models of…
