Downward circulation may not affect MACS with CD34 mAb because antibodies generally have a 10,000-fold higher ligand-binding affinity than TCRs (Matsui em et al

Downward circulation may not affect MACS with CD34 mAb because antibodies generally have a 10,000-fold higher ligand-binding affinity than TCRs (Matsui em et al. /em , 1991). In agreement with these findings, Streptamer, the only detachable reagent, exposed significant T cell growth in the 1st week after MACS. Sorting TCR and tCD34 gene-engineered T cells…

Macrophages constitute up to 10% of infected cells in HIV-infected individuals (11, 12)

Macrophages constitute up to 10% of infected cells in HIV-infected individuals (11, 12). and cellular HIV restriction factors (Tetherin and APOBEC3G/3F) in HIV-infected macrophages. These findings indicated that IECs might act as an important element in GI innate immunity against HIV contamination/replication. vesicular transcytosis (4, 5). Central to the capacity of IECs to maintain barrier…